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Moreover, the deregulation of IL-6 production has been implicated in a wide range of autoimmune diseases, including rheumatoid arthritis, diabetes, depression, and multiple myeloma 35

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that is to say, Glu accumulates when vit B12 increases, since cysteine is not available for the gamma-glutamylcysteine synthetase to act to form gamma-glutamylcysteine, as shown in Fig

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