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GPX1, one of the most abundant members of the GPX family, is widely expressed in almost all cells and is distributed in the cytoplasm, mitochondria and peroxisomes [13]

doi: 10.1172/jci.insight.122525 85

The exhaustion of Treg cells in the body can lead to severe autoimmune diseases, and the lack of CTLA-4 is the key molecule causing this problem (199202)