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In particular, lack of early response appears to be strongly indicative of subsequent nonresponse [2], failure to achieve remission [3], and higher rates of treatment discontinuation [4]

The results obtained should provide high quality scientific evidence of use when taking treatment decisions in the primary healthcare centres, while allowing patient preference of administration route to be taken into consideration

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They act as powerful antioxidants, protect against cellular damage from free radicals, and can improve gut health and energy levels