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Despite extensive research, disease-modifying treatments remain elusive, with current management primarily focusing on symptom control

These findings suggest that plasma PKM2 may serve as a clinically useful biomarker candidate for assessing disease activity

This would be of regulatory significance as renal damage is an endpoint of concern to environmentalists and researchers in this field, as it is likely to lead to population decline

The only treatments include stopping the selenium exposure and providing supportive care depending on symptoms of individual patients

"Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials" (PDF)