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In mouse models, copper deficiency impairs cardiac function, manifesting as reduced diastolic and systolic performance alongside a diminished inotropic response to beta-adrenergic stimulation, which compromises the heart's ability to adapt to stress [206]

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A review of the effects of collagen treatment in clinical studies (includes RA trial summary)

Now, lets take a closer look at the relationship between these fat-soluble nutrients and hyperthyroidism