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MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY During myocardial ischemia and reperfusion, both myocardial GSH and the GSH/GSSG ratio within the ischemic tissues are reduced, and the extent of the myocardial injury is inversely dependent on the myocardial GSH content

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Hence, therapeutic strategies aimed at enhancing glial GSH synthesis or exporting ability may help modulate glial-immune phenotypes, reduce microglial activation, and slow progressive CNS degeneration in neurodegenerative diseases (Figure 2)

There is currently no cure for MS, but there are a variety of treatments available that can help manage symptoms, slow disease progression, and improve quality of life

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