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Medicine 98:e16163

Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: An update for clinicians

Some also serve specialized roles, functioning as biosensors (e.g., glucose monitors) or drug delivery systems (e.g., coated vascular stents)

Goss, P

Conclusion: Our results suggest PAI-1 is required for FOLFOX-mediated NF-B activation, which then further induce PAI-1 expression and release in a feedforward manner, exerting autocrine and paracrine effects to cause liver injury