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Description

Piperine targets different drug resistance mechanisms in human ovarian cancer cell lines leading to increased sensitivity to cytotoxic drugs

During this process, astrocyte-derived type I collagen is upregulated, coinciding with the onset of neuronal death

However, its total heme titer reached 239.2 7.2 mg/L, comprising 87.7 1.7 mg/L of intracellular heme and 151.4 5.6 mg/L (63.3%) of extracellular heme during the fed-batch fermentation (Zhao et al