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The sooner you diagnose your skin cancer, the less invasive the treatment will be and the better your prognosis

1 5 , 12, 13 In some, there is increase in basal cell pigmentation with no increase in melanocyte numbers, reminiscent of an ephelide, whereas others resemble lentigines with pronounced rete ridge elongation and increased numbers of melanocytes (Fig

In addition to classic Spitz nevi, which are recognized as benign proliferations, certain Spitz tumors demonstrate extensive pleomorphic features indistinguishable from melanoma and are termed Spitzoid melanoma

Correspondingly, melanocytes isolated from nonlesional skin and cultured in vitro have lower levels of catalase, heme-oxygenase (HO-1), superoxide dismutase 2 (SOD2), and ubiquinone expression [53,60]