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Murthy CR, Rama Rao KV, Bai G, et al

KEYWORDS: Tight junction, paracellular permeability, barrier function, intestinal epithelium, gastrointestinal disease Introductory note Tight junction is the key determinant of barrier function in various epithelial cell types

In one case study, a 5 month old breastfed infant of a vegan mother (who actually received a prenatal vitamin containing 96% of her daily needs of B12 throughout her pregnancy) presented with many of the above symptoms and required a 19 day hospital stay to stabilize

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These factors activate downstream pathways such as TrkB/PI3K/AKT and Wnt/-catenin, thereby promoting NSC proliferation, neuronal survival, synaptic remodeling, and angiogenesis [144, 184] (Fig