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98 Park et al also found that the pro-apoptotic effect of apigenin on endometriosis cells and the inhibitory effect on cell proliferation were achieved through modulating MAPK and PI3K/Akt signaling pathways

Similarly, the increase observed in various metabolites participating in the phosphocreatine system (creatine, creatinine) and niacin metabolism (niacinamide, N1-methyl-4-pyridone-3-carboxamide), which are responsible for managing the energy pool (i.e., ATP, NADPH), further supports profound failures in catabolism

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2,5,6 In addition to older age, tinnitus is more likely in those with hearing loss, a history of loud noise exposure, and head or neck trauma

Di Ciaula A, Garruti G, Fruhbeck G, De Angelis M, De Bari O, D QHW,