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Prog Neurobiol 2015;125:26-46

Learn how GLP-1 therapy may affect digestion and how smaller meals, hydration and individualized nutrition habits may support digestive comfort

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It incorporates key modifications, including 14E/17R mutations to stabilize an -helical segment via a salt bridge, multiple proline substitutions (25P, 28P, 29P) to reduce -sheet formation, and N-terminal C20 fatty diacid lipidation for reversible albumin binding (Kruse et al

USE IN SPECIFIC POPULATIONS Pregnancy Fetal/Neonatal Adverse Reactions Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Injectafer) which may cause fetal bradycardia, especially during the second and third trimester