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Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations

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When these affinity-enhancing mutations were added to full-length rat amylin, all three mutated rat amylin analogs showed enhanced potency for amylin receptor 1/2 activation by 5- to 10-fold compared to endogenous rat amylin and a clinical drug pramlintide (Figure 9A, 9B and Table 3)

These cells line the blood vessels and are considered to be integral to forming new blood vessels during wound healing

10.1002/aja.1001270402 187 PfeifferT.PollS.BancelinS.AngibaudJ.Krishna InavalliV