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HMGA1 knockdown restores ULK1 expression and enhances LC3B lipidation, although autophagosome maturation may remain impaired

Science 354 , 572577 (2016)

This change to an amorphous state from a crystalline state is an advantage from a formulation perspective

Figure 5 In order to identify processes and functions that may be transcriptionally affected by SLIM1, we tested for over-representation of Gene Ontology (GO) terms and KEGG pathways in three sets of class 1 genes at 37 DAS and 44 DAS: class 1 genes that are positively regulated by SLIM1, class 1 genes that are negatively regulated by SLIM1, and all class 1 genes regardless of the response direction to SLIM1 ( Figure 6 )

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