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Additionally, ATF3 promotes macrophage polarization towards the M2 phenotype, enhances the expression of anti-inflammatory factors such as Arg-1 and PPAR, but suppresses M1 markers (such as iNOS and TNF-), thereby alleviating inflammatory responses and facilitating tissue repair (142)

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Like any supplement, you should check with your healthcare provider before using it

The results showed that after transfection with siSTAT3, GHK-Cu treatment showed a synergistic effect on the inhibition of inflammatory factors (Figures 8AE)