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These include Pine part, Beewax, and grapeseed, which helps to soothe and moisturize the skin, and vitamin C, which helps to protect the skin from environmental stressors and prevent aging

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KEGG pathway analysis revealed that upregulated DEGs were enriched in Metabolic pathways, Alanine, aspartate and glutamate metabolism, Chemical carcinogenesis-DNA adducts, Steroid hormone biosynthesis, Biosynthesis of amino acids, Retinol metabolism and Metabolism of xenobiotics by cytochrome P450 (Fig

In view of the diversified role on EVs, this review highlights the crucial involvement of EVs in pathogenesis and progression of CF lung disease, focusing on role of EVs in induction of inflammation, oxidative stress and activation of EV-miRNA mediated signaling pathways leading to influence CF pathophysiology