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Neuro-enteric phenotypes as a conceptual framework Marked inter-individual variability in gastrointestinal tolerance, metabolic adaptation, and performance is a consistent feature of exercise responses, yet it is poorly explained by cardiorespiratory fitness or baseline microbial composition alone

Parenteral administration ensures rapid and effective absorption, especially in patients with impaired gastrointestinal absorption

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But, those on blood thinners should be careful about how B12 could affect their treatment

its an active area of scientific discussion, not a settled finding