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116,238,239 High-dose intravenous (IV) steroids may also be useful in patients who do not respond to conventional treatment

What sets ARA-290 apart mechanistically is that it does not simply mask pain

Moisture barriers (ointments, salves, and films), topical corticosteroids, antiseptics, and antifungal agents, as well as moisture-regulating dressings like self-adaptive wound dressing, may be used as part of local treatment to protect the peri-wound and maintain its healthy functionality ( When the leg veins fail to properly push blood back up to your heart, venous ulcers (open sores) can develop

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