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The gene expression of SNCA and LRRK2 which can cause PD was found to be reduced by the cooperative interactions of these two drugs

Knockdown of Nrf2 reduces melanocyte viability but not the viability of keratinocytes and fibroblasts, indicating that melanocytes are preferentially dependent on Nrf2 (Arowojolu et al., 2017)

In addition to movement disorder, different non-motor symptoms such as dementia, psychosis and depression are observed in patients, which increase in late stages of disease