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These derivatives have been used in clinical settings for autoimmune disorders and are generally well-tolerated

doi: 10.1038/s41420-022-01212-0 101 WangWGreenMChoiJEGijnMKennedyPDJohnsonJKet al

Although a serials of control groups were set, including DHA-SNO + X-ray, DHA@M + X-ray, and BA-N@M + X-ray, the inherent dynamic crosstalk and reciprocally regulation between oxidative stress, lipid metabolism [62], and ferroptosis pathways, makes it challenging to precisely quantify the individual contributions of specific mechanisms (NO/ONOO - generation, GSH depletion, and lipid metabolic interference) to the overall therapeutic outcome

KDM2B regulates intermediary metabolism by targeting the expression of a host of metabolic enzymes, including those in the SGOC, glutamate, and GSH metabolism

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