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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

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This finding suggests that OD-based or simple connectivity-centric PTN planning alone may not effectively safeguard mobility equity or balanced development

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Medically reviewed by Mark Ziats, MD, PhD This article was medically reviewed by Mark Ziats, MD, PhD