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In populations who cannot exercise due to frailty, physical disability, or cardiovascular limitations, MOTS-c represents one of the most compelling candidates in the emerging class of pharmacological exercise mimetics

Gastrointestinal Health Given that BPC-157 was originally discovered in gastric juice, its GI effects are among the most extensively studied

The unfolded protein response (UPR) is triggered when an excessive amount of misfolded proteins accumulate in the ER, which can be caused by overnutrition, increased reactive oxygen species (ROS), or proinflammatory cytokines ( Figure 2A )

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Their production increases during cell necrosis