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*Correspondence: Zhenmin Liu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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We also report findings of ITC treatment in five preclinical studies, including 4 in vivo and 1 in vitro models of ASD

Activities of the control enzymes GSH peroxidase (GPx) and lactate dehydrogenase (LDH) were determined using published methods [22,23] with 1 mM sodium azide, 3.0 units of yeast GR (Sigma), 1 mM GSH, 0.02 mM DTT, 0.0007% (w/v) H 2 O 2 , and 100 M NADPH in the GPx assay and 10 M sodium pyruvate and 100 M NADPH in the LDH assay