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Benefits: Activation of the serotonergic and dopaminergic centers in the brain by increasing brain-derived neurotrophic factor (BDNF), which supports the survival of existing neurons as well as the growth of new neurons and synapses Antidepressant-like and anxiolytic-like properties without addictive side-effect profile Improvement of depression and ADHD associated symptoms Improved sleep patterns and calming of racing thoughts Improves circulation helps protect the heart from damage after a stroke or heart attack Improvement of both long and short-term memory May help alleviate pain by preventing the breakdown of enkephalins, which regulate the pain response Side Effects: Transient headache or feeling of heartbeat in the ear Dosage and Route: Semax is compounded into sublingual tablets, which dissolve under the tongue

Study endpoints include epithelial-barrier function, tight-junction protein expression, inflammatory signaling, and mucosal tissue remodeling in models of intestinal inflammation, increased permeability, and chemically induced gastrointestinal injury

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