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Alternatively, the mRNA of seleno-GPxs ranking high in the hierarchy (like GPx4) is stabilized through the interaction of a selenium responsive positive regulator like nucleolin with their 3-UTR (Fig

Neurosci Lett 500(2):139143

Most reported side effects of these peptides in studied doses are mild (injection-site irritation, transient sleep or vivid dreams, headaches), but longterm, largescale human safety dataespecially for longevity useremain limited