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Since the mid-1980s praziquantel (Figure S1) has been the drug of choice for schistosomiasis

(5) C Laustrup Mller, K Raun, M Lambert Jacobsen, et al (2011) Characterization of murine melanocortin receptors mediating adipocyte lipolysis and examination of signalling pathways involved Molecular and Cellular Endocrinology, 2011 Jul 20, Volume 341 (Issues 1-2), Pages 9-17

An imidazole nitrogen atom in His-18 is the main binding site for Cu 2+ (Magr et al., 2016)

devised a reactive oxygen species (ROS)-sensitive polymer (PHPM) for the co-encapsulation of esculomol (ES) and copper, resulting in the formation of nanoparticles (NP@ESCu) ([129]