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The genetic or pharmacological restoration of GPX4 suppresses neutrophil ferroptosis and abrogates downstream autoimmunity, underscoring GPX4 as a checkpoint that constrains iron-driven inflammation (206, 217)

In the following sections we review what is known about the conformational properties of antibody Fv regions and how they may impact on cytokinergic activity

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[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Voron T., Colussi O., Marcheteau E., Pernot S., Nizard M., Pointet A.-L., Latreche S., Bergaya S., Benhamouda N., Tanchot C., et al