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Three areas create the clearest red flags: The subdeltoid bursa which reacts with inflammation when vaccine material enters the space, often creating significant swelling The rotator cuff tendons which produce more pain during lifting motions or outward rotation The joint capsule which can stiffen rapidly if trauma or inflammation develops These structures do not follow the timeline seen in normal arm soreness

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Research has demonstrated that Dihexa binds to HGF with remarkably high affinity (Kd = 65 picomolar) and acts as an allosteric modulator, potentiating HGF activity even at subthreshold concentrations

5e and Supplementary Data 2)