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PLOS One 11, e0165130

189 Management of DRPN focuses on optimizing glycemic control to prevent further nerve damage

Avoid Stimulants Stimulants, such as caffeine, alcohol, or energy drinks, can worsen adrenal fatigue symptoms by: Overwhelming the adrenals through increased release of stress hormones

Also, though used as a last resort, the spleen might be surgically removed in cases where the red blood cells are so affected that the spleen removes them from the blood too quickly for other treatments to compensate

Moreover, obesity has been revealed to reduce the effectiveness of TNF inhibitors, resulting in lower chances of achieving remission or low disease activity (58, 60)