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However, due to the limited structural information that can be obtained from the isotopologue patterns or MS/MS spectra of small metabolites, the annotation of unknown metabolites within these subnetworks remains a challenge

The promoter regions of the identified genes are enriched with various cis-acting elements that play roles in plant growth and development, stress response, and hormone signaling

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GPx14 in mice and humans and GPx6 in humans out of eight known GPx isoforms in mammals contain selenocysteine at their active sites and thus are categorized as selenoproteins

17,18,19,20,21 The only phenotypes that were causally associated with HU were gout and kidney disease