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Both are dominated by gastrointestinal adverse events nausea, constipation, diarrhea, vomiting that are mostly mild-to-moderate and dose-related

Safety and activity of anti-PD-L1 antibody in patients with advanced cancer

Additionally, the brain needs to release more follicle stimulating hormone (FSH) to stimulate these abnormal eggs to mature and typically does so even in the luteal phase prior to the cycle being tracked, resulting in a shortened follicular phase and early ovulation

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