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For instance, high grade bronchial dysplasia produces greater paracrine and autocrine IGF than benign bronchial epithelial cells [110], suggesting the IGF system has an early role in lung cancer development

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some bacterial phylotypes exhibited significant S-soil specificity in both ST20 (Southwest China) and ST22 (Northeast China), while some fungal phylotypes showed S-soil-specificity in both oak-associated shiro (ST20) and pine-associated shiro (ST21)

While it can improve the surface appearance of skin over time, it does not fundamentally rebuild deeper tissue structures

Representative tissue specimens were embedded in paraffin, sectioned at 4 m, stained with hematoxylin and eosin (H&E), and evaluated by light microscopy using an Olympus 71 digital camera and an Olympus BX51 microscope (Japan) acquiring digital images saved as uncompressed 24-bit RGB TIFF files