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Studies of model compounds have established a range of 6.0 - 7.0 for the intrinsic p K a of the histidine side chain

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doi: 10.1038/s41580-018-0074-2 256 ZengDHeSMaCWenYSongWXuQet al

When you consume vitamins and minerals orally, only a portion is absorbed by the digestive systemsometimes as little as 20-30%and the rest may be excreted