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Notably, glucose metabolic imbalance contributes to increase the oxidative stress, impairing ATP production, thus providing a hint for the exacerbation of neurodegeneration 25

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The expression level of individual genes was normalized to that of the housekeeping gene RPLP0 (NM_001002

Zinc can activate the Nrf2/HO-1 pathway, increase the contents of GPX4, SOD and GSH, reduce the levels of lipid peroxides, MDA and ROS, and effectively reverse the behavioral and structural changes after SCI