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Interestingly, 1-week post-treatment, GFAP expression was reduced to ~49% in untreated and ~28.8% in LPC-treated slices, suggesting mitigation of the astroglial response

In AD research, researchers employed methylation arrays alongside PCR-based methylation-sensitive high-resolution melting (MS-HRM) analysis to examine blood DNA from 56 patients with late-onset Alzheimers disease (LOAD) and 55 healthy controls (59)

Diabetes 59 , 24532464 (2010)

On the other hand, certain lncRNAs function as transcriptional repressors by blocking the binding or recruitment of transcription factors and RNA polymerase to gene promoters