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Aging is fundamentally a progressive decline in organ function and accumulation of pathological damage across multiple systems, necessitating long-term, multidimensional interventions for effective mitigation (46)

Quadri et al., 2013

A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells