glutathione-mediated reduction of hydrogen peroxide Deciphering the mechanism glutaredoxin-catalyzed roGFP2 redox sensing reveals a ternary complex with glutathione for protein disulfide Glutathione and peroxisome redox homeostasis

Moreover, a model of Hutchinson-Gilford progeria syndrome (HGPS) shows larger nucleoli, increased ribosomal biogenesis and an overall increase in protein translation levels (Buchwalter and Hetzer, 2017), thus ascribing a potential functional connection between this aging biomarker and the global increase in protein synthesis that is observed over aging

That this finding was only observed in the DLPFC (and not the ACC) in our cohort is in line with research observing frontal cortical thinning in blast exposed veterans (59), decreased activity (60), and white matter damage (61) in the PFC following mTBI

Fang JY, Mikovits JA, Bagni R, Petrow-Sadowski CL, Ruscetti FW

doi: 10.1017/S003118209600858X 69 NausCWABoothMJonesFMKemijumbiJVennervaldBJKariukiCHet al

1B), we further performed particle subtraction on this domain to improve the resolution to 2.65 , and the resulted reconstruction enabled the fitting of the individual atomic models for DDB1, DDA1 (PDB: 6DSZ) and DET1 (AlphaFold model: AF-Q7L5Y6-F1), allowing for the modelling of most of the complex 34