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These results evoke the speculation that higher dTTP level in T315I-Bcr-Abl-32D cells might prevent DNA replication stress to affect JMF4073 sensitivity

Additionally, glutathione plays a critical role in detoxification and the removal of free radicals, thereby affecting gsh content and status

Thyroglobulin antibody is associated with increased cancer risk in thyroid nodules. Thyroid : official journal of the American Thyroid Association vol

It arises from an abnormally expanded CAG trinucleotide repeat encoding the elongated polyglutamine (polyQ) within exon 1 of Huntingtin ( HTT ) gene, which results in the production of toxic mutant huntingtin proteins (mHTT) that accumulate in neurons, particularly in the striatum and cortex ( HTT gene normally contains 10 to 35 CAG trinucleotide repeats, while HD patients exhibit more than 36 repeats