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Jo et al., Chemoresistance of cancer cells: requirements of tumor microenvironment-mimicking in vitro models in anti-cancer drug development

The transcript profile of the cys-c1 mutant showed lowered levels of transcript related to ethylene signalling and metabolism, e.g

Additionally, hypoxia-only methods are commonly used to investigate hypoxic brain biochemistry 52,54 and are established models used to generate seizures in neonatal rats