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Doctors call it being nic sick when too much nicotine makes you nauseous immediate, short-lived and socially understood as oops, too much. What we dont name as sickness is what happens when the nausea never comes when the damage takes decades to interrupt a life: reduced lung capacity, cardiovascular strain, chronic inflammation and eventually diseases like COPD that turn breathing into a task

J Rheumatol 30 : 12221226 Washio M et al

When exposed to tobacco smoke, the rats arteries had difficulty expanding for about 30 minutes

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