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doi: 10.1093/nar/gkab1038 Summary Keywords HNF4, CAR dysfunction, liver, sepsis, acute phase response, metabolism Citation Van Dender C, Timmermans S, Roes M, Hellemans M, Moens E, Nuyttens L, Claes M, Roman B, De Bosscher K, Vandewalle J and Libert C (2025) HNF4 contributes to hepatic CAR dysfunction in polymicrobial sepsis

Levodopa has been used to treat PD for more than 50 years, and it is still considered the therapy of choice

demonstrated that a methionine-restricted diet inhibits tumor growth in multiple mouse models and enhances both the number and cytotoxic function of tumor-infiltrating CD8 + T cells (as indicated by upregulated expression of Granzyme B and Interferon-gamma) (47)

However, there is a lack of follow-up studies on the radioprotective potential of ebselen by the scientific community