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Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

Subsequent mechanistic studies revealed that phosphorylated FOXO1 relocates from the nucleus to the cytoplasm, resulting in a decrease in its transcriptional activity

doi: 10.1016/j.bcp.2023.115598 Ahmed, Jamila, Walker, Andrew A., Perdomo, Hugo D., Guo, Shaodong, Nixon, Samantha A., Vetter, Irina, Okoh, Hilary I., Shehu, Dalhatu M., Shuaibu, Mohammed N., Ndams, Iliya S., King, Glenn F

Overall, these findings suggest that TAB interventions may have significant implications for addressing reproductive dysfunctions associated with elevated MGO/AGEs levels

This specialty area is also used for aneurysm patients who were initially admitted to the Neurological Intensive Care Unit