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While single-cell metabolomics is a powerful tool for profiling individual cell metabolism in tissues, the technically demanding isolation and preparation of tissue samples for metabolic analysis without introducing artifacts or altering the native metabolic state remain significant challenges

Kosanovic D, Tian X, Pak O, et al

Furthermore, these findings could be dependent on other environmental factors, such as oxygen level or temperature

PMID: 32 LinLYuWZhangWLiSHuSJiangBet al

Sequencing was performed on the Illumina HiSeq 2500 platform (Illumina, San Diego, CA, USA) with a strand specific paired end library (2 125 bp) using v4 chemistry