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Long duration does not mean that improvement is impossible, but treatment usually needs a structured approach that addresses both nerve sensitization and contributing factors

They have also been linked to improving mood and alleviating symptoms of depression by playing a vital role in synthesizing and metabolizing serotonin

Generally, we recommend one PRP injection with the possibility of a second injection at 6-12 weeks, depending on the response

However, typically, patients experience even more benefits in the coming days and weeks

When site reactions did occur, they were typically mild erythema or transient induration, resolving without intervention within 2448 hours