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Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

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Because glutathione is broken down in the gut when taken orally, IV administration bypasses this loss, theoretically delivering more intact glutathione to tissues

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We derived model inputs from published data and used a drug price of $19,011/year in base-case

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