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172 Interestingly, peroxisomes may contribute to ferroptosis through synthesizing PUFA-ePLs, and 786-O tumor xenografts can evade GPx4 knockout induced ferroptosis in mice by downregulating PUFA-ePLs

Therefore, considering antioxidants as promising agents in the prevention of AFs complications might decrease the deterioration of hepatic cells and prevent the development of liver cancer, though this claim requires further clinical assessment

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doi:10.4103/1735-1995.175154