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Deficiency of this manganese and copper results in the deficiency of SOD, which leads to accumulation of the superoxide molecule

B., Sacanell, C

Jun 2007;61(3):147-152

In the biotechnology industry, a secondary enzyme such as formate dehydrogenase has been explored for regenerating NADH from NAD + that will provide a reduced cofactor for reductase/dehydrogenase reactions (Hummel and Grger, 2014)