interaction of chloroacetamide electrophiles with cellular glutathion NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation Identification, optimization, and structural elucidation

Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C terminal Hydrolase L3 bioRxiv Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Sulfamate Acetamides as Self Immolative Electrophiles for Covalent Ligand Directed Release Chemistry Journal of the American Chemical Society Electrophilic compound screening identifies GPX4 dependent ferroptosis as a senescence vulnerability Nature Cell Biology Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles ScienceDirect

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