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Psychiatry 113 TakahashiK.YanaiS.TakisawaS.KonoN.AraiH.NishidaY.et al (2019)

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Change in sulfhydryl homeostasis of the cell, especially the steady state of glutathionylation of specific regulatory proteins, modulates various pathways of signal transduction, shifting the cell state from survival to death

Is treatment becoming too complex for the carer and impossible to administer to the patient, damaging the carer-cat bond and leading to an unacceptable caregivers burden