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65 Additionally, empiric IC/BPS strategies in those CP/CPPS patients have demonstrated clinical symptomatic improvement

Another study showed that benfotiamine prevents stress-impaired adult hippocampal neurogenesis, as well as stress-induced bodyweight loss, anxiety-like behavior and oxidative stress in mice [75]

Surgical interventions represented the largest proportion at 30% (28 studies), with a strong emphasis on minimally invasive techniques such as endoscopic discectomy (NCT06615518) and disc replacement procedures (NCT06989632)

101 It is inhibited by its product 2,3-BPG and by inorganic phosphate, and it is activated by 2-phosphoglycerate and by increased pH levels

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